Realizing the promise of chemical glycobiology

StemCONN: Realizing the Promise

On April 3, 2013, the fourth biennial StemCONN conference took place at the Omni Hotel at Yale in New Haven, Connecticut. This conference featured talks by scientists from across the country who are currently at the forefront of stem cell research, as well as talks by Edison Liu, President and CEO of the Jackson Laboratory, and Jonathan Rotherberg, PhD, a Yale alumnus and Ion Torrent Systems Fo...

Chemical glycobiology.

Chemical tools have proven indispensable for studies in glycobiology. Synthetic oligosaccharides and glycoconjugates provide materials for correlating structure with function. Synthetic mimics of the complex assemblies found on cell surfaces can modulate cellular interactions and are under development as therapeutic agents. Small molecule inhibitors of carbohydrate biosynthetic and processing e...

Sustaining and realizing the promise of telemedicine.

Chemical approaches to glycobiology.

Glycans are ubiquitous components of all organisms. Efforts to elucidate glycan function and to understand how they are assembled and disassembled can reap benefits in fields ranging from bioenergy to human medicine. Significant advances in our knowledge of glycan biosynthesis and function are emerging, and chemical biology approaches are accelerating the pace of discovery. Novel strategies for...

Realizing the promise of personalized medicine.

Scientific advances have begun to give doctors the power to customize therapy for individuals. However, adoption of this approach has progressed slowly and unevenly because the trial-and-error treatment model still governs how the health care system develops, regulates, pays for, and delivers therapies. Aspinall, the president of Genzyme Genetics, and Hamermesh, chair of a Harvard Business Scho...